An Alternative to Traditional Sample Size Determination for Small Patient Populations

Sample size determination for logistic regression

The problem of sample size estimation is important in medical applications, especially in cases of expensive measurements of immune biomarkers. This paper describes the problem of logistic regression analysis with the sample size determination algorithms, namely the methods of univariate statistics, logistics regression, cross-validation and Bayesian inference. The authors, treating the regr...

Comparing two Formulas of Sample Size Determination for Prevalence Studies

Background and purpose: Sample size and its determination is one of the most important problems in health researches. Calculating sample size for prevalence studies is one of the common questions of sample size topics. Minimum sample size with least complexity is desirable in order to achieve the basic goal of these studies. This study aims to compare two formulas of sample size calculation for...

Sample size determination.

Scientists who use animals in research must justify the number of animals to be used, and committees that review proposals to use animals in research must review this justification to ensure the appropriateness of the number of animals to be used. This article discusses when the number of animals to be used can best be estimated from previous experience and when a simple power and sample size c...

Sample size determination

On Sample Size Determination

One of the questions most frequently asked of a statistician is: how big should the sample be? Managers are anxious to obtain an answer to this fundamental question during the planning phase of the survey since it impacts directly on operational considerations such as the number of interviewers required. There is no magical solution and no perfect recipe for determining sample size. It is rathe...